专题研讨与学术报告

专题研讨与学术报告

当前位置: 首页 > 专题研讨与学术报告 > 正文
【学术报告】 Adaptive Group Sequential Design Methods for Clinical Trials
日期:2018-06-01 点击:
报告题目                                           :Adaptive Group Sequential Design Methods for Clinical Trials      
报告时间:2018年6月5日,星期二,下午16:00-17:00
报告地点:数学与统计学院北五楼319会议室
报告人:程怡 教授

美国Indiana University South Bend数学科学系


报告摘要:

The presentation includes two parts. The first part is a brief introduction of adaptive group sequential designs in clinical trials. The second part presents a specific adaptive design, namely, Bayesian group sequential designs, summarized as follows.

A clinical trial requires decisions about how an experiment will be conducted. The process is often dynamic; therefore, Bayesian formulation provides a powerful mechanism for running such a process.

The decision theoretical approach considers the consequences of each possible designing parameter and selects ones to maximize the expected utility.  While utility setting and statistical decisions depend on the goals of the experiment, certain choices may be restricted by available resources and ethical considerations.

The Bayesian adaptive group sequential designs also have the flexibility of allowing interpretation of the results along frequentist lines, in addition to maximize the utility function. The frequentist error rates can be established so that the desired properties can be maintained for regulatory settings.


报告人简介:

Yi Cheng 教授,博士毕业于美国University of Minnesota,专业为统计学。曾任职于美国的Purdue University以及Northwestern University,现任职于美国Indiana University South Bend。多年来从事临床试验设计方面的研究工作,取得了丰富的研究成果,在Biostatistics,  Biometrika, Biometrics等统计方面的权威期刊上发表高水平论文数十篇。多次应邀访问德克萨斯大学、康奈尔大学和西北大学等,并在统计学国际会议作邀请报告。多次获得IUSB杰出教学奖,IU教师研究基金,Frederic Bachman Lieber纪念奖等荣誉。




版权所有:西安交通大学数学与数学技术研究院  设计与制作:西安交通大学数据与信息中心
地址:陕西省西安市碑林区咸宁西路28号  邮编:710049